Prof. Dr. med. Christian Seidl

Prof. Dr. med. Christian Seidl

Ärztlicher Leiter, Abteilungs- / Bereichsleiter und ärztliche Funktionsträger

DRK Blutspendedienst Baden-Württemberg – Hessen gGmbH
Institut für Transfusionsmedizin und Immunhämatologie Frankfurt am Main
Sandhofstraße 1
60528 Frankfurt am Main
Tel.: 069 6782-232 / 203
E-Mail

Sekretariat:
Kristina Echt
Tel.: 069 6782-444
E-Mail


Beruflicher Werdegang

2004 - 2005

Tissue Typing Representative bei Eurotransplant (ET) als Kooperationspartner des Transplantationszentrum am Universitätsklinikum Frankfurt am Main (GFM)

Mitglied im Bundesverband der Sachverständigen für Abstammungsgutachten – BVAG

Mitglied der Kommissionen für Organtransplantation, Stammzelltransplantation und Qualitätssicherung der Deutschen Gesellschaft für Immungenetik (DGI)


Ausgewählte Publikationen

  • Seidl C, Saraiya C, Osterweil Z, Fu YP, Lee JS. Genetic complexity of regulatory mutant defective for HLA Class II gene expression. J Immunol 1992; 148: 1576-1584.
  • Gärtner H, Seidl C, Luckenbach C, Seifried E ,Ritter H. Genetic analysis of a sarcoma accidentally transplanted from a patient to a  surgeon. N Engl J Med 1997;  335: 1494-1496.
  • Seidl C, Siehl J, Ganser A, Hofmann W-K, Fischer M, Kirchmaier CM, Hoelzer D, Seifried E. Platelet glycoprotein expression in patients with myelodysplastic syndrome. Thromb Res 2000; 100: 27-34
  • Seidl C, Körbitzer J, Badenhoop K, Seifried E, Hoelzer D, Zanelli E, Kaltwasser JP. Protection against severe disease is conferred by DERAA-bearing HLA-DRB1 alleles among rheumatoid arthritis patients carrying the HLA-DQ3-DR4 and HLA-DQ5-DR1 haplotypes. Hum Immunol 2001; 62: 523-529.
  • Becker S, Tonn T, Füssel T, Uhrberg M, Seifried E, Seidl C. Assessment of Killer Cell Immunoglobulin-like Receptor (KIR) expression and corresponding HLA-class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA-class I ligands. Hum Immunol 2003; 64(2): 183-193.
  • Koehl U, Beck O, Esser R, Seifried E, Klingebiel T, Schwabe D, Seidl C. Quantitative analysis of chimerism after allogeneic cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with fluorescence detection: the Frankfurt experience. Leukemia 2003; 17(1): 232-236.
  • Richter R, Süsal C, Köhler S, Qidan S, Schödel A, Holschuh L, Brzoska M, Asbe-Vollkopf A, Büttner S, Betz C, Herrmann E, Gauer S, Seifried E, Geiger H, Seidl C, Hauser IA. Pre-transplant HLA Antibodies Detected by Single Antigen Bead Assay are a Risk Factor for Long-Term Kidney Graft Loss Even in the Absence of Donor Specific Antibodies. Transpl Int. 2016 Sep;29(9):988-98. doi: 10.1111/tri.12786. Epub 2016 Jun 14
  • Becker PS, Suck G, Nowakowska P, Ullrich E, Seifried E, Bader P, Tonn T, Seidl C. Selection and expansion of natural killer cells for NK cell-based immunotherapy. Cancer Immunol Immunother. 2016 Apr;65(4):477-84. doi: 10.1007/s00262-016-1792-y. Epub 2016 Jan 25
  • Arnold ML, Bach C, Heinemann FM, Horn PA, Ziemann M, Lachmann N, Mühlbacher A, Dick A, Ender A, Thammanichanond D, Schaub S, Hönger G, Fischer GF, Mytilineos J, Hallensleben M, Hitzler WE, Seidl C, Spriewald BM.  Anti-HLA alloantibodies of the IgA isotype in re-transplant candidates part II: Correlation with graft survival. Int J Immunogenet. 2018 Jun;45(3):95-101. doi: 10.1111/iji.12363. Epub 2018 Mar 25.

Bücher/Buchbeiträge: 

  • Seidl C, Seifried E. Immunogenetics: Clinical and diagnostic aspects of the human leukocyte antigen (HLA) system. In: Lothar Thomas (Ed.) Laboratory Pathology. Indications and Assessment of Laboratory Results for Clinical Diagnostics. 1st Englisch Edition (2016), p1532-1537
  • Seidl C, Seifried E (Editoren). European Blood Inspection Project (EuBIS)  Inspection/audit training manual and guide on common criteria and standards for the inspection of blood establishments. Manual and guide published under the Public Health Programme of the European Commission. Revised Edition 1.0.1, Juni 2016.
     

Studien

  • Projekt - EU-Q-Blood-SOP‚ Grant agreement no. 2004217. Konzeption eines pan-europäischen SOP-basierten Qualitätsmanagementsystems (EU-Q-Blood-SOP) für den Bereich der Transfusionsmedizin’ Co-funded by the European Commission - Directorate C - Public Health and Risk Assessment www.equal-blood.eu
  • Projekt EuBIS (EU-Blood-Inspection), Europäische Qualitätsmanagement- und Inspektions-Standards für Blutspendeeinrichtungen in Zusammenarbeit mit der Europäischen Kommission, Directorate General SANCO. www.eubis-europe.eu
  • Project CATIE (Competent authority training of inspectors for blood establishment in Europe (CATIE) under the auspices of the European Commission – Public Health Programme www.catie-europe.eu
  • Collaborating Partner EU Optimal Blood Use Project EU Optimal Blood Use Project ‘on the optimal use of blood components and best therapeutic practice across Europe, through sharing of information on how to establish such a programme’ A800151 - area 2.2.4
  • Collaborating Partner Joint Action VISTART “Vigilance and Inspection for the Safety of Transfusion, Assisted Reproduction and Transplantation” (Grant Agreement No. 676969)  3rd EU Health Programme funded by the European Commission, DG Sante and CHAFEA 
  • Technical Expert EU Twinning Project (Germany/Malta) MT 04/IB/OT/04-TL „Upgrading the National Blood Transfusion Service to Quality Standards as specified in Directive 2002/98/E
  • Projekt Klinische Forschergruppe - Chimärismus, Autoimmunität und Toleranzinduktion durch Transplantation hämatopoetischer Stammzellen

Mitgliedschaften

Deutsche Gesellschaft für Transfusionsmedizin und Immunhämatology (DGTI)

Deutsche Gesellschaft für Immungenetik (DGI)

Deutsche Transplantationsgesellschaft (DTG)

European Federation for Immunogenetics (EFI)

International Society for Forensic Haemogenetics (ISFH)

International Society for Blood Transfusion (ISBT)